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The type of DNA damage response after decitabine treatment depends on the level of DNMT activity
Introduction 5-Aza-2′-deoxycytidine (decitabine, AzadC) and 5-azacytidine (Azacytidine, AzaC) are cytosine analogues that covalently trap DNA methyltransferases (DNMTs) and therefore belong to the compound class of hypomethylating agents (HMAs) (1, 2). …